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DenysMAAndingRTubaroAAbramsPEveraertK.Lower urinary tract symptoms and metabolic disorders: ICI-RS 2014

Fungal dysbiosis (the mycobiome) is increasingly recognized in UC

Extra care is a must to avoid flare-ups

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Confocal microscopy (Leica SP8), scanning electron microscopy (SEM, JEOL JSM-6610LV), transmission electron microscopy (TEM, JEM-1400 Flash), and atomic force microscopy (AFM, Bruker Dimension Icon) were employed to analyze the grafts surface and ultrastructure

Under the synergistic stress of ROS accumulation and Ca 2+ overload, this condition eventually induces sustained opening of the mitochondrial permeability transition pore (mPTP) ( Pathological opening of the mitochondrial permeability transition pore (mPTP) promotes the release of pro-apoptotic molecules such as cytochrome c (Cyt C) and Smac/DIABLO into the cytosol, thereby initiating the caspase-9mediated intrinsic apoptotic cascade and triggering cardiomyocyte death (Zorov et al., 2014)