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doi: 10.1016/S0140-6736(72)90676-9 3 RuwendeCKhooSCSnowRWYatesSNKwiatkowskiDGuptaSet al

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Localized pain, infection, inflammation, tenderness, swelling, redness, and bleeding/bruising have been reported nationally, but these effects extremely rare among our patients

[8] also reported elevated oxidative stress and inflammation in lipedema tissue, and our metabolomic data support the existence of a dysregulated redox environment potentially sustained by aberrant AKT1 activation

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