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Nat Biomed Eng , 1 , Padera, T

Abbreviations MetS: Metabolic syndrome IGF-1: Insulin-like growth factor CVD: Cardiovascular disease T2D: Type 2 diabetes RAS: Protooncogene protein P21 NAFLD: Non-alcoholic fatty liver disease OSA: Obstructive sleep apnea HDL: High density lipoprotein TG: Triglyceride PI3K: Phosphatidylinositol-4,5-bisphosphate 3-kinase AKT: Protein kinase B GLUT: Glucose transporter FA: Fatty acid FFA: Free fatty ACID IGF-1R: IGF-1 receptor IGFBP: Insulin-like growth factor binding protein IRS: Insulin receptor substrate KO: Knock out LDL: Low density lipoprotein VLDL: Very low density lipoprotein GH: Growth hormone HOMA: Homeostasis model assessment ROS: Reactive oxygen species References Executive Summary of The Third Report of The

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In 2-DE immunoblot analysis, liver, kidney, and urine proteins (600 g, 300 g, and 3 g, respectively) obtained from untreated rats were subjected to identify MUP isoforms using pH 47 NL (24 cm) strips and 11.5% sodium dodecyl sulfate- polyacrylamide gel electrophoresis (SDS-PAGE)

doi: 10.1016/j.bbrc.2004.08.045 119 LeeS