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Painter and Burkitt first elucidated this connection after noting the striking disparity in incidence between British society and sub-Saharan populations

Thus, contrary to what is seen in NER, patients with tumors deficient in MMR show resistance to cisplatin 13

27 We also found that FBX8 inhibited the proliferation, invasion and metastasis of CRC by promoting the degradation of GSTP1

Kirejev, V., Kandoth, N., Gref, R., Ericson, M

fumigatus , as demonstrated by the observation that the absence of mcsA encoding methylcitrate synthase (involved in amino acid degradation) reduced in vivo virulence [56]

Estrogen and vaginal pH/colonization: A 2025 study assessed how estradiol (E2) levels correlate with vaginal pH and candida growth, finding that higher E2 levels can correlate with lower, more acidic pH