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doi: 10.1007/s00421-017-3710-1

Family members say Bens swelling was progressing by the second

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Metformin and vitamin B 12 deficiency Metformin-induced vitamin B 12 deficiency was reported as early as 1971 when Tomkin et al

Also, pentadecapeptide BPC 157, given peripherally, could affect sphincter function through serotonin (51, 52) or dopamine (in the same dose-range that BPC 157 prevented/reversed catalepsy or stereotypy and all concomitant gastrointestinal lesions) (53-56), likely providing a particular balance between peripheral and central effects (57)

Strict vegetarians and vegans are at a greater risk of B12 deficiency because B12 is mainly found in meat, fish and dairy products