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Additionally, other researchers have observed deposition of type I collagen in the smooth muscle cells of coronary arteries of CD38 KO mice, but found that CD38 deficiency did not affect the expression of type I collagen protein and mRNA, indicating that CD38 regulates the degradation of type I collagen by inhibiting autophagosome and lysosomal fusion [34]

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There is some evidence for the association between maternal ID and preterm delivery [16], low birth weight [17], possible placental abruption, and increased peripartum blood loss [18]

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NICE notes that pernicious anaemia is the most common cause of Vitamin B12 deficiency in those aged 40-70, with an average onset age of 60 in white people and 50 in black people, although it can affect black women at a younger age