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[129] , methotrexate-loaded SLNs were prepared to enhance skin penetration and reduce keratinocyte proliferation

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Glutathione-Disrupted Biofilms of Clinical Pseudomonas aeruginosa Strains Exhibit an Enhanced Antibiotic Effect and a Novel Biofilm Transcriptome

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doi:10.1056/NEJMoa2108891

Whereas most patients, including P3 and P4 in the current study, had a very similar and recognizable phenotype at birth, the siblings from family 1, and to a lesser extent P5, lacked most of the typical facial features at birth and in infancy, and they did not initially display pronounced skin fragility