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Li et al observed that endothelial cell pyroptosis is the dominant form of cell death in the initial phases of DMED development [89], and suppressing NOD-like receptor thermal protein domain associated protein 3 expression can significantly reduce pyroptotic activity in diabetic penile tissue of rats, enhancing the vascular endothelial function [91]

BaP modulates aberrant DNA methylation or promoter hypermethylation in various tumor suppressor genes, which alters gene expression and contributes carcinogenesis

The others will be used as access points for other arthroscopic tools

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