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Following addition of NanoBRET Nano-Glo Substrate, donor emission (450 nm) and acceptor emission (610 nm) were measured using an Envision instrument (PerkinElmer)

L., Hong S., Jin M., Ostaszewski B., et al

15A) [225]

Pain is a frequent complaint and can be debilitating

At present, the compound is undergoing a phase III clinical trial (NCT03254446) to assess its effectiveness in mitigating cardiovascular risk in individuals with diabetes, dyslipidemia, and hypertension [76, 77]

Potential assay procedures for testing mycotoxin induced nephrotoxicity As mentioned above, the most widely used biomarkers in other fields, are KIM-1, NAG, NGAL, Cystatin-C and 2-MG (Table 1)