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Modulating the GSH-GCL axis or targeting cysteine redox signaling represents a promising therapeutic avenue for IPF (Fig

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Among these, nanotechnology-based approaches hold significant promise for enhancing therapeutic efficacy by circumventing resistance mechanisms

Theres evidence that polyunsaturated fatty acids like linoleic acid may act directly and indirectly on 5-alpha reductase by 1) reducing inflammation, and 2) altering lipid bilayers in cell membranes to decrease 5-alpha reductase formation