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Therefore, the modulation of HDACs may serve as an intriguing therapeutic approach for curing epilepsy
Daridorexant has been approved by NICE (2023) for the treatment of long-term insomnia when all of the following apply: Cognitive behavioural therapy for insomnia is not available or has not been effective

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At the same time, we are humbled by the many therapies that have shown promise in phase II trials only to prove no better than placebo or sham in phase III trials
This further underscores the necessity of elucidating the molecular mechanisms of ferroptosis and developing targeted therapeutic strategies