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Although lipid peroxidation products (e.g., 4-HNE, MDA) and systemic iron parameters are altered in bodily fluids of AD patients (e.g., cerebrospinal fluid, blood), these markers lack disease and cell death modality specificity, as similar changes can occur in other neurodegenerative disorders or systemic pathological conditions

The no-observed-effect level (NOEL) was 125 mg/kg, the lowest-observed-effect level (LOEL) was 675 mg/kg (Til et al., 1988)

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