Combination of GSTM1 active and GSTT1 active decreased the risk of ASD (OR = 0.126, 95%CI: 0.0290.547, p = 0.006), as well as the combination of GSTT1 active and GSTP1 llelle (OR = 0.170, 95%CI: 0.0290.992, p = 0.049)
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Transient induction of microsomal enzymes leading to liver damage and nodular hyperplasia produced by safrole and ponceau mx
It functions by inhibiting osteoclast activity, stimulating type I collagen synthesis, promoting osteoblast maturation, and regulating gene transcription, DNA, and histone methylation (151)

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