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It also reduced the release of pro-inflammatory cytokines, including TNF-, IL-6, and IL-1, which were triggered by ethanol exposure, improved energy homeostasis in the ileum, and reversed the downregulation of mRNA and protein expression of key tight junction proteins in the ileum, specifically ZO-1, Claudin-1, and Occludin, thereby restoring their functional integrity

2.7 Pathway and protein-protein interaction enrichment analysis The biological process and pathway enrichment analysis were done in Metascape (version 3.5) (Zhou et al., 2019)

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Biological and therapeutic effects of honey produced from the Malaysian Tualang tree

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Comparative differentiation was made between antioxidant activities in animals based on pretreatment with CRE, with CRE-AgNPs, and with respective controls