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DKK1 expression is also inhibited due to the upregulation of certain miRNAs, such as miR-375 and miR-376 (Taube et al., 2013

That selectivity is precisely why it is chosen as the amplifier in this blend rather than a messier alternative

Finally, 0.5 mg of larazotide t.i.d., but not the higher doses, improved symptoms in CeD patients with persistent symptoms despite following a gluten-free diet (99)