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Recent studies further highlight the role of metabolic reprogramming in tubular repair, with defective fatty acid oxidation in aged kidneys exacerbating post-IRI maladaptive repair (Mylonas et al., 2021)

Colchicine, H2-receptor antagonists, metformin and proton pump inhibitors

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Beclin1 is known to have an important role in the nucleation of phagophores and maturation of the autophagosomes, which occur in further stages of autophagy