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APAP-induced senescence is most prevalent among cells at the perinecrotic area, where NAPQI-cys levels are high

These changes are irreversible unless upstream TGF-1 signaling is modulated and ECM degradation mechanisms (e.g., MMP activity) are restored

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Back Couzin-Frankel, J (6 Sept 2023) 'Her work paved the way for blockbuster obesity drugs

Last, researchers monitored visual function by measuring contrast threshold with and without glare