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Phytochemicals such as CGA, berberine, ganoderic acid, costunolide, piperine, and cardamonin not only reshape microbial communities but also influence their metabolites, gut barrier function, mucosal immunity, and even central nervous system signaling

These receptors can be found throughout the brain, thyroid, adrenal glands, fat tissue, pancreas, and muscular heart tissue

Metabolites 11 , 44 (2021)

10.1021/acs.jnatprod.5b00246 36 CerdB.CernJ

It helps the cells in your gut grow and repair themselves, which is key for good digestion and absorbing nutrients

The effect on mitochondrial function supports its clinical use in other related conditions