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Patients in this cluster showed higher rates of nearly every queried symptom and comorbidity than other clusters, and as expected, the most prevalent symptoms are the core symptoms of the disorder: fatigue (98.9%), PEM (97.4%), brain fog (93.6%), unrefreshing sleep (95.2%), memory problems (82.4%), feeling of weakness (87.3%), sore/painful muscles (87.0%), insomnia (76.1%), and headache/migraine (79.8%)

Variations in ACL size, shape, and insertion points can affect the distribution and activity of these growth factors, impacting the ligaments ability to repair and adapt to mechanical loading

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In brief, both tesamorelin and sermorelin effectively increase GH and IGF-1, albeit at different rates