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et al., oral administration of Lactiplantibacillus plantarum Y15 to STZ + HFD-induced T2D mice improved fasting glucose, HbA1c, and HOMA-IR levels, reduced pro-inflammatory cytokines (IL-6, TNF-, among others), decreased the abundance of LPS-producing bacteria, and promoted SCFA-producing populations

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Reduced estradiol concentrations have important clinical implications, given the critical role of estradiol on bone density, body composition, and sexual function in men [24,25,26]

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Its liquid nasal format enables precise volumetric handling for experimental protocols requiring peptide administration via mucosal surfaces or simulation thereof