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In hepatocytes and adipocytes it reduces the activity of key lipogenic enzymes: Acetyl-CoA carboxylase (ACC) , a key step in fatty acid synthesis Fatty acid synthase (FAS) , the enzyme creating long chains of fatty acids Lipoprotein lipase (LPL) in adipocytes, reduces uptake of circulating triglycerides into fat cells Imagine it as turning valves in a pipeline, you close the inflow (lipogenesis), open the outflow (lipolysis)

doi: 10.1056/NEJMoa050330 357

Bells Palsy symptoms were present for 10 months with no improvement

Ethics Statement A study protocol was approved by the Ethics Review Committee of Aga Khan University hospital

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