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Epigenetic modifications have been reported to induce a series of changes in gene expression and protein levels that result in mitochondrial abnormalities and neuronal apoptosis and lead to PD (Zhang et al., 2021), long non-coding RNAs ( Mitochondrial Quality Control in Parkinsons Disease Quality control mechanisms are essential to maintaining a healthy mitochondrial network and cell homeostasis, especially to dopaminergic neurons

Our results indicated that juglone had IC 50 values of 8.7 M when using 2 mM substrate concentrations (Figure 6)

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Addressing both the growth stimulation and the underlying cause of follicle damage creates a more comprehensive approach than either mechanism alone would provide

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The chronicity of the disease along with treatment modalities might have played a significant role in the outcome of our study as the subjects included in diabetic group were selected without considering their glycemic control status