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Merck Manuals Online Medical Library for Healthcare Professionals

Metabolomics of mitochondrial disease

The antioxidant effect of DEC-containing serum on pigmented full-thickness human skin model To evaluate the antioxidant potential of the DEC-containing serum under oxidative stress induced by MGO and UV irradiation, we analyzed ROS levels using fluorescence staining and measured key antioxidant markersincluding Nrf2, SOD, and GSH-Px1through semi-quantitative immunofluorescence in a pigmented full-thickness human skin model