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Titration protocols therefore hold a dose until nausea and other gastrointestinal effects settle rather than escalating on a fixed target date

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Could improve exercise tolerance and endurance rather than subjective alertness. In insulin-resistant states, MOTS-C improves glucose utilization, which can reduce post-prandial crashes and chronic low-energy states

Sun exposure and topical moisturizers can help as well (Heier 2011