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Blocking the interaction between apolipoprotein E and A reduces intraneuronal accumulation of A and inhibits synaptic degeneration

J Diabetes Mellit 12(4):187203 Bhattacharya S, Gachhui R, Sil PC (2013) The prophylactic role of D-saccharic acid-1, 4-lactone against hyperglycemia-induced hepatic apoptosis via inhibition of both extrinsic and intrinsic pathways in diabetic rats

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This contrasts with other forms like cyanocobalamin, which the body must convert into methylcobalamin or adenosylcobalamin before use