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In another series of experiments, apoE3 Christchurch was effective in preventing tau pathology and associated neurodegeneration when human fibrillar tau was injected in an amyloid mouse model of AD [194]

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7 , eabe9444 (2021): Jaroentomeechai, T

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28 When DNA repair pathways become disrupted, particularly those involving base excision repair and nucleotide excision repair, accumulated DNA damage triggers p53-mediated responses, which can induce cell cycle arrest, apoptosis, or premature differentiation of MSCs, directly contributing to the graying phenotype