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Additionally, intracellular calcium levels regulate ERK activation, and elevated calcium concentrations have been shown to enhance ERK signaling

Wentzel AS, Janssen JJE, de Boer VCJ, van Veen WG, Forlenza M, Wiegertjes GF

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Efficacy and safety of olanzapine for the prophylaxis of chemotherapy-induced nausea and vomiting (CINV) as reported in phase I and II studies: a systematic review