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Circ Res 2018;122:62438

J.DAlessandroA.SzczepiorkowskiZ

Astrocytes acquire iron via the divalent metal transporter 1 (DMT1) pathway, while ceruloplasmin located on the astrocyte membrane effectively inhibits lipid peroxidation and ferroptosis through protein-protein interactions or regulating the oxidation of Fe 2+ to Fe 3+ (Jeong and David, 2003)