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Some clinicians who are trying to help their patients may find the information upsetting because it reflects a paradigm shift in understanding of antidepressants

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This degradation releases NF-B from the IB complex, facilitating its translocation to the nucleus, where it binds to the promoter region of target genes, including Il-6 , to activate their transcription 29

doi: 10.1016/j.bbrc.2016.10.086 34 YanBAiYSunQMaYCaoYWangJet al