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Effects of aging on the biomechanical properties of the lung extracellular matrix: dependence on tissular stretch

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4a), we assumed that MEK1/2 phosphorylation might be induced by inhibition of AKT activation

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GSH deficiency makes cells more sensitive to oxidative stress and can cause degeneration of epithelial cells 50,51

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A: Aging involves parallel processes: collagen degradation, oxidative stress, inflammation, and reduced cellular repair

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