glutathione transferases a structural perspective

glutathione transferases a structural perspective S-transferase: versatile and dynamic enzyme Possible Approaches to Drug Delivery

Name: glutathione transferases a structural perspective S-transferase: versatile and dynamic enzyme Possible Approaches to Drug Delivery
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Possible Approaches to Drug Delivery via Glutathione Transferase Proteins and Chitosan Sjdin 2023 Israel Journal of Chemistry Wiley Online Library GST Tag Definition & Data RCSB PDB 1AQW: GLUTATHIONE S TRANSFERASE IN COMPLEX WITH GLUTATHIONE RCSB PDB 1R5A: Glutathione S transferase Structural Biology Platform Facilitates Discovery of Glutathione S Transferase Inhibitors, Offering Novel Pathways for Drug Development WuXi Biology The role of glutathione S transferases in human disease pathogenesis and their current inhibitors PMC

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Thus, in this work, we showed that inactivation of the marRAB regulon in antibiotic-resistant cells reversed the acidification and decreased the resistance

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Therefore, exogenous glutamine can stimulate drug uptake to the point where uptake outpaces the combined rates of -lactamasedependent drug degradation and drug efflux, such that the intracellular concentration of antibiotic exceeds the threshold required to kill the cell