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Furthermore, in Con A-treated mice, the expression of caveolin-1 (Cav-1) was prominently suppressed, while fer-1, the ferroptosis inhibitor, could rescue Cav-1 expression and inhibit the generation of reactive nitrogen species (RNS)

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Such important mechanisms, nonetheless, fail to fully account for the in vitro and in vivo immunologic actions of DMF (39)

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