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In summary, whether in hoof DD or other skin infections, the underlying process involves disruption of skin/hoof microbial homeostasis under external stress, leading to loss of protective microbial function and dominance of pathogenic microorganisms

Human induced pluripotent stem cells (iPSCs) represent a versatile platform for investigating key questions in neurodevelopmental and neurodegenerative diseases, with broad potential for both basic and translational research

For example, there was no significant difference in the clinical scores between CIA-modeled Sting1 +/- mice and wild-type mice on days 27, 30, and 33 after the first immunization, although the clinical scores of both groups were increased

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For example, the HRV 3C protease recognizes and cleaves the sequence Leu-Glu-Val-Leu-Phe-Gln--Gly-Pro, enabling the separation of the GST tag from the target protein