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So, these agents target the underlying pathophysiology of PD, unlike traditional symptomatic treatments like MAO-B inhibitors, dopamine agonists, or COMT inhibitors

Even though other relevant options are available, such as animal models or ex vivo models, in vitro models offer higher experimental flexibility and reproducibility, making them a valuable tool for the understanding of pathophysiological mechanisms of several diseases, such as CVDs

or another condition, like fibromyalgia or chronic fatigue syndrome, may be present

10.1016/s0092-8674(00)81554-8 Cell 13 BrennaA.OlejniczakI.ChavanR.RippergerJ

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Relevance of corpus callosum splenium versus middle cerebellar peduncle hyperintensity for FXTAS diagnosis in clinical practice