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Serum brain-derived neurotrophic factor level is reduced in antidepressant-free patients with late-life depression

Slowly increased in frequency and intensity along with pressure in the arm and then day 4 woke up in extreme pain unable to move the arm

doi: 10.1523/JNEUROSCI.3411-17.2018 97 JinRLiuLZhangSNandaALiG

Problem: you should have escalated to 4mg at week 5, 8mg at week 9, and potentially 12mg at week 13