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Despite recognition of the essential roles of folate in DNA synthesis and neural tube defect prevention, its metabolic pathway remained poorly characterized

found that when three lines of human cancer cells (SH-SY5Y neuroblastoma cells, U937 histolytic cells, breast cancer cells) were incubated in culture with 1 to 10 nanomolar GHK, the programmed cell death system (apoptosis) was reactivated and cell growth inhibited [26]