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This shift is manifested by increased glucose consumption and lactate production in DCs, which supports the rapid production of proinflammatory cytokines, such as IL-6, IL-8, MIP-1, and TNF-, thereby amplifying acute systemic inflammation[21, 22]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 581.Zhou Y, Li M, Zhou K, Brown J, Tsao T, Cen X, et al

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The role of glutamate in neuronal ischemic injury: the role of spark in fire