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Non-specific Symptoms These symptoms may or may not be directly linked to TD: Lower Energy Level, Endurance, and Physical Strength : General decrease in overall energy and physical capabilities

Liblau, et al

96 This suggests that exosomes enriched with alcohol-associated mtDNA damage may contribute to injurious cross-talk between the alveolar epithelium and macrophages

[DOI] [PMC free article] [PubMed] [Google Scholar] 6.Bai L, Ren H, Liang M, Lu Q, Lin N, et al

Loss of the mitochondrial NAD + -dependent deacetylase sirtuin 3 results in mTORC1 activation, induction of mTORC1-dependent CAD phosphorylation and increased pyrimidine synthesis