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Description

A novel CD133- and EpCAM-targeted liposome with redox-responsive properties capable of synergistically eliminating liver cancer stem cells

miR-125b controls monocyte adaptation to inflammation through mitochondrial metabolism and dynamics

Prasad AS, Bao B, Beck FW, Kucuk O, Sarkar FH

Mitochondrial function is required for extracellular ATP-induced NLRP3= inflammasome activation

It was proposed that these cardioprotective effects are due to its inhibition of pro-hypertrophic signaling molecules, improvement of myocardial calcium handling, and reduction of oxidative stress and inflammation (Salehi et al., 2018)