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Although the pooled analysis did not show a statistically significant association, a consistent trend toward increased breast cancer risk, particularly in C282Y homozygotes, was observed

This protective role helps maintain cellular integrity and reduces the risk of chronic diseases associated with oxidative damage

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Numerous studies have linked folate intake to a reduced risk of some cancers, including colorectal cancer, while folate deficiency has been shown to increase the risk of cancer

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Nrf2 transcriptionally activates GGT [29], which plays a key role in glutathione homeostasis by breaking down extracellular glutathione into its constituent parts, which can be taken up by the cell for intracellular glutathione synthesis [30]