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During retinal development, DNMTs regulate the differentiation of retinal progenitor cells into photoreceptor cells, with DNMT deficiencies leading to impaired retinal morphology and severe visual deficits (Singh et al., 2017)

If your levels of cysteine and methionine are low, the B12 has nothing to do once you intake it

ClinicalTrials.gov: NCT03198572

10.1016/j.freeradbiomed.2023.03.022 110 ShiH.ZhouP.GaoG.LiuP

Final Thoughts vitamin B12 overdose is extremely rare , taking excessive amounts through supplements or injections may cause mild side effects in some individuals

For instance, verteporfin liposome is the first FDA-approved drug for treating AMD [214]