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Environmental changes lead to oxidative stress, resulting in disruptions in plant development and potentially leading to plant death (Sharma et al

In summary, additional research is needed to understand the intricate molecular mechanisms of p53 in regulating senescence in order to optimize the efficacy and safety for clinical applications

For example, curcumin has been evaluated in Phase II clinical studies in pancreatic cancer and colorectal cancer patients, where oral doses up to 8 g/day demonstrated acceptable safety but limited systemic exposure, highlighting pharmacokinetic challenges

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So I do, I do NAD

doi:10.1177/17534666231170800 28