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As these enzymes are encoded by genes with the wild-type allele occurring in most individuals, a normal or extensive metabolizer receives or inherits two copies of the normal wild-type allele from each parent and thus respond normally to drugs at standard doses

Deters A, Zippel J, Hellenbrand N, Pappai D, Possemeyer C, Hensel A

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Retrospective study of clinical features and prognosis of edaravone in the treatment of paraquat poisoning

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