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Moreover, in a recent proteomic approach, several enzymes involved in glutathione production show high values in those strains ( in-vitro artemisinin-resistant strains overexpress GR ( This model implies that glucose may be the primary source of carbon for the TCA cycle, agreeing with the mutants obtained by Ke et al (Rosenthal and Ng, 2020)

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The resistance of lipoproteins to lipid peroxidation is modulated by both dietary fatty acids and antioxidants

They produce metabolites, particularly short-chain fatty acids like butyrate, that regulate immune activity, maintain the integrity of the gut lining, and influence the immune behavior in tissues far from the gut itself

16S rRNA sequence analysis demonstrated that administering a high choline diet to mice increased the relative abundance of Lactobacillus and Lachnospiraceae_UCG-002 , while decreasing the proportion of Bacteroides