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Rapid and body weight-independent improvement of endothelial and high-density lipoprotein function after roux-en-Y gastric bypass: role of glucagon like peptide-1

IGFBPs can function extracellularly but are also internalized into cells and can be transported into the nucleus

For cell culture experiments mouse TM3 Leydig cells and GC-1 spg spermatogonia cells were utilized

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Song JY, Jang HK, Kim BS

Conclusion: The MAFLD group did not demonstrate an elevated risk of all-cause, cardiovascular, or cancer mortality when compared to the MA without fatty liver group