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GPX4, a Se-dependent enzyme, defends cells by neutralizing lipid hydroperoxides

All studies were approved by the University of Washington IACUC

[DOI] [PMC free article] [PubMed] [Google Scholar] Lucena S

Culturing HSCs in conditioned medium from M1 macrophages upregulated the expression of fibrosis-related genes (CTGF, TIMP1) and YAP-regulated genes (ANKRD1, CYR61)