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Moreover, given the redundancy in microglial signaling pathways, targeting a single mechanism like TRPM2 may allow compensatory responses that support long-term central nervous system health while dampening harmful inflammatory outputs

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Other National Data Sources Considered We also checked in on: NDEWS has no public trend data for their real-time 911 calls, and ODMap has weekly data from police and EMS but prohibit public access

Medications as Endocrine Disruptors Diethylstilbestrol One of the most well-known pharmaceutical EDC exposures was as a consequence of diethylstilbestrol (DES) consumption by pregnant women in an attempt to mitigate the risk of miscarriage, preterm birth, and other pregnancy-related complications (Rumph et al., 2020)

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Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein