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Severe hypoglycaemia-induced microglial inflammation damages microvascular endothelial cells, leading to retinal destruction

Another paper in Ageing Research Reviews found that NAD may replenish NAD levels in aged tissues and exhibit beneficial effects against aging and aging-related diseases

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However, its important to keep the following in mind: ALA is not a substitute for statins or other prescription cholesterol medications The lipid-lowering effect is generally modest, especially in healthy individuals or those already on treatment Dose and duration matter most benefits are seen at 6001,200mg/day over 8+ weeks Antioxidant and anti-inflammatory effects: moderate evidence ALA is best known for its antioxidant activity and thats not just in theory

Research shows nitrate supplementation improves time trial performance by 2-3% in trained cyclists and increases time to exhaustion by up to 20% in endurance tests