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It is rare at GFRs higher than 80 mL/min, but as the GFR falls, the severity of the anemia worsens and its prevalence increases: almost 90 percent of patients with a GFR less than 30 mL/min are anemic

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The parietal cells of the stomach secrete a glycoprotein called intrinsic factor, which takes B12 from the R-factor and carries it to the last part of your intestine, called the ileum, for absorption of B12

Delivery typically takes a few business days depending on location and processing time

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It may also reduce inflammatory markers in joint tissue