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Not only is most fish low in fat, the mainly refined carbohydrates.30 fat in fish also has high amounts of omega-3 fats (see pp

Overexpression of ferroptosis suppressor protein 1 (FSP1) or cytosolic GPX4 stimulates the genesis of ferroptosis-resistant CD8 + T cells without compromising their function, while the depletion of ferroptosis sensitivity-promoting enzyme acyl-CoA synthetase long-chain family member 4 (ACSL4) protected CD8 + T cells from ferroptosis but impaired antitumor CD8 + T cell response (Drijvers et al., 2021)

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Glutathionylation associated with PDCE2 was indeed observed upon LPS treatment in both cases, but was compromised in recombinant expression systems with LPS-treated THP-1 cells where the lipoamide-linking lysine residues in PDCE2 were mutated

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10.1186/s11658-022-00320-0 85